Samantha Who?

Sunday, August 17
7.30pm

Overjoyed that somebody must have liked her, Sam jumps at the chance to assume her role as bridesmaid in a friend’s wedding. However she shows up to the wedding only to learn she’s been uninvited by the bride. At first dejected – and then motivated by the challenge of vindication – Sam sets out to apologize and be re-accepted by the bride, as a result leaving Dena in the dust yet again.

Sunday, August 10
7.30pm

Samantha (Christina Applegate) awakens in the hospital and is surrounded by family and friends. The only problem is that she has no idea who they are – or who she is. Sam has retrograde amnesia, which allows her to fully function in the world but leaves her with no personal memories. Most people would deem this disorder a curse, but Sam may come to call it a miracle when she discovers what a horrible person she was before the accident.

Monday, May 5
9.30pm

While Samantha continues her affair with Todd — who’s still seeing a clueless Chloe — she becomes convinced that Regina is having a rendezvous of her own. Meanwhile, Andrea toys with the idea of opening up a coffee shop with Dena.

Monday, May 12
9.30pm

As Samantha’s relationship with Todd begins to heat up, she decides to put it on hold until he breaks up with girlfriend Chloe (guest-star Kiele Sanchez, Lost), as he had promised. But Sam begins to think that Chloe is lying to Todd about her sick aunt in order to play the sympathy card. Meanwhile, Regina and Andrea bump heads over how to plan Samantha’s birthday party.

Monday, April 28
9.30pm

Trying to prove she has moved on since her breakup with Todd, Sam asks Craig (guest star Jerry O’Connell, Carpoolers) – a complete stranger – to accompany her to Todd’s photo gallery exhibit. But Sam soon learns that she may have already crossed paths with Craig at some point in the past, and not in a positive way. Meanwhile, Howard discovers that one of Todd’s photos on display features his daughter in a not-so-positive light.

Monday, April 21
9.30pm

Sam sets Dena up on a date with her boss in order to persuade him to shut down a construction project that will destroy an endangered butterfly habitat. Meanwhile, Sam can’t understand why Todd has been ignoring her ever since they shared a passionate kiss.

Monday, April 14
9.30pm

Samantha is stunned when Winston Funk (guest star Timothy Olyphant, Live Free or Die Hard), the wealthy co-owner of the real estate firm, asks her to marry him. Since Sam knows that Andrea is completely smitten by him, she is worried that this could ruin their friendship.

Monday, April 7
9:30 p.m.

Samantha Who? returns, and Samantha is forced to move back into the apartment when she discovers that she could be evicted for subletting it to Todd, who has just invited his new girlfriend, Chloe (Kiele Sanchez, Lost), to move in with him. Meanwhile, when Sam fails to show up for a makeover night with her mom, Regina and Dena end up bonding and having a girls’ night at the house.

Christina Applegate returns to primetime in the new comedy Samantha Who?, airing Mondays at 9:30 p.m. ET/PT beginning October 15, only on A-Channel.

Applegate shows off her comedic talents as the naughty and nice Samantha Newly, a woman who awakens from a coma with amnesia – and the chance to start a new life. Samantha Who? joins a hilarious Monday night line-up on A-Channel beginning with Scrubs at 8 p.m. ET/PT, The Big Bang Theory at 8:30 p.m. ET/PT and Two and a Half Men at 9 p.m. ET/PT. Monk airs Mondays at 10 p.m. ET/PT following Samantha Who?

In the series premiere, Samantha awakens in the hospital and is surrounded by family and friends. The only problem is that she has no idea who they are – or who she is. Sam has retrograde amnesia, which allows her to fully function in the world but leaves her with no personal memories. Most people would deem this disorder a curse, but Sam may come to call it a miracle when she discovers what a horrible person she was before the accident.

As she sets out to rediscover herself, Sam is forced to rely on an eclectic bunch of friends and family. Regina (Jean Smart, 24, Designing Women) and Howard (Kevin Dunn, Transformers, Dave) appear to be loving parents when they’re not downplaying the fact that Sam hasn’t spoken to them in two years. Her supposed best friend, Dena (Melissa McCarthy, Gilmore Girls), is sincerely supportive, until her real best friend, party girl Andrea (Jennifer Esposito, Crash, Spin City), exposes the fact that Dena hasn’t seen or spoken to Sam since the seventh grade. Making things even more awkward, Sam has no recollection of her live-in boyfriend, Todd (Barry Watson, What About Brian, 7th Heaven).

Sam quickly discovers she was a horrible person, vain, selfish and potentially surrounded by far more enemies than friends. She makes a conscious decision to improve herself moving forward. She vows to make better choices, even though her instincts may not always steer her in the right direction. She begins with Frank (Tim Russ, Live Free or Die Hard, Star Trek: Voyager), the doorman at her apartment building. Sam never gave him the time of day before, but after making an effort to simply say hello to him, she discovers an incredibly observant and unlikely confidant.

Sam will need to continue to piece together things from her past to guide her in discovering who she is… or was. After all, sometimes to get to the end of the story, the only place to start is the beginning.